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GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO
Descriptors Found:
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DeCS
Descriptor
English
:
GTP-Binding Protein alpha Subunits, Gi-Go
Descriptor
Spanish
:
Subunidades alfa de la Proteína de Unión a GTP Gi-Go
Descriptor
Portuguese
:
Subunidades alfa de Proteínas de Ligação a GTP Gi-Go
Synonyms
English
:
Gi, Inhibitory G-Protein
G-Protein, Inhibitory Gi
G-Protein, Gi-Go alpha Family
Tree Number:
D08.811.277.040.330.300.200.100.200
D12.644.360.375.100.200
D12.776.157.325.332.100.200
D12.776.476.375.100.200
D12.776.543.325.100.200
Definition
English
:
A
family
of heterotrimeric
GTP-binding protein alpha subunits
that were originally identified by their ability to inhibit
ADENYLATE CYCLASE
. Members of this
family
can couple to beta and gamma G-protein subunits that activate
POTASSIUM CHANNELS
. The Gi-Go part of the name is also spelled Gi/Go.
Indexing Annotation
English
:
DF: G PROTEIN INHIB GI
History Note
English
:
2004(1997); for GUANINE NUCLEOTIDE-BINDING PROTEIN GO use GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO (NM) 1997-2003
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
33044
Unique Identifier:
D019206
Occurrence in VHL
:
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